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10x Genomics Single-Cell Lab Technician

BMKGENE Europe · Münster, North Rhine-Westphalia, Germany

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Key ResponsibilitiesPerform end-to-end single-cell sequencing workflows, including sample processing, single-cell dissociation, single-nucleus preparation, cell sorting, quality assessment, and library preparation.Execute and optimize single-cell experiments using platforms such as 10x Genomics, PARSE, or other single-cell technologies.Conduct molecular biology experiments including PCR, qPCR, nucleic acid extraction/purification, and NGS-related workflows.Handle human and mouse tissue samples and optimize protocols for challenging samples to improve experimental performance and data quality.Operate laboratory instruments including flow cytometers (FACS), cell counters, PCR/qPCR systems, and other molecular biology equipment.Analyze experimental results, maintain accurate laboratory records, prepare reports, and communicate findings with internal teams and customers when required.Troubleshoot experimental issues, improve laboratory workflows, and contribute to the development and validation of single-cell methodologies.Collaborate with research teams and support the training or supervision of junior team members when needed.RequirementsA Master’s degree with 1–3 years of relevant hands-on laboratory experience.Hands-on experience with single-cell sequencing platforms (10x Genomics or equivalent) and related experimental workflows.Experience inSingle-cell suspension preparation and tissue dissociation (human/mouse tissues)Single-nucleus extraction/preparationFlow cytometry/FACS operationMolecular biology techniques including PCR, qPCR, purification, and NGS workflowsExperience with protocol optimization, troubleshooting, and laboratory SOPs.Familiarity with organoids, recombinant AAV, screening, or low-input molecular assays is a plus.Basic experience with data analysis tools (e.g., Prism, Spotfire, or equivalent) and interest in bioinformatics is preferred.Good communication skills and ability to work collaboratively in a research environment.Willingness to travel when required.Proficiency in English (written and spoken).