Chief Medical Officer
Vastu Vihar Biotech Pvt. Ltd. · Bodh Gaya, Bihar, India
Apply & track with Apply EdgeAbout the Company
exRNA Therapeutics Ltd. is a biotechnology and gene-targeted drug development company focused on developing safe, innovative, and ethically driven therapeutic solutions for diseases with significant unmet medical needs. The company operates across preclinical drug discovery, translational research, genetic analysis, and RNA-based and antisense oligonucleotide therapeutics, with a focus on translating scientific discoveries into clinically meaningful treatments. Through expertise in RNA biology, molecular biology, drug discovery, preclinical research, and translational science, exRNA Therapeutics aims to advance next generation therapies that target underlying disease mechanisms and contribute to the future of precision and personalized medicine. Position Summary : We are seeking an accomplished and visionary Chief Medical Officer (CMO) to provide medical and clinical leadership across the company's therapeutic development programs.The CMO will play a critical role in translating the company's scientific and preclinical innovations into clinically relevant development programs, providing strategic direction across clinical development, translational medicine, patient safety, medical affairs, and regulatory interactions.The ideal candidate will bring a strong combination of clinical expertise, drug development experience, scientific understanding, and executive leadership, with the ability to work closely with R&D, Regulatory Affairs, Preclinical, CMC, Business Development, and executive leadership teams.
Key Responsibilities
1. Medical & Clinical StrategyDevelop and lead the company's overall medical and clinical development strategy.Provide medical leadership for therapeutic programs from preclinical development through clinical development and commercialization.Define clinical development priorities, endpoints, patient populations, and development pathways.Assess clinical feasibility, therapeutic potential, benefit-risk profiles, and unmet medical needs.Provide medical input into product development plans and organizational strategy.2. Translational MedicineLead the transition of promising preclinical discoveries into clinically relevant therapeutic programs.Work closely with R&D and preclinical teams to establish translational strategies and development milestones.Evaluate preclinical data and determine clinical relevance and readiness.Support biomarker, pharmacodynamic, patient-selection, and precision-medicine strategies.Ensure scientific findings are effectively translated into clinical development plans.3. Clinical DevelopmentOversee the design and execution of clinical development programs and clinical trials.Provide strategic input into clinical protocols, study design, endpoints, and statistical considerations.Guide selection and oversight of clinical research organizations, investigators, and clinical partners.Ensure clinical programs are conducted according to applicable GCP, ethical, and regulatory standards.Monitor clinical progress, safety, efficacy, and development risks.4. Regulatory & Health Authority EngagementProvide medical leadership in regulatory strategies and interactions with relevant health authorities.Support preparation and review of clinical and regulatory submissions.Participate in regulatory meetings and scientific discussions where medical expertise is required.Ensure clinical development strategies remain aligned with evolving regulatory expectations.5. Scientific & R&D CollaborationPartner with the CEO, CSO, R&D leadership, and scientific teams to evaluate new therapeutic opportunities.Provide clinical and medical perspectives during pipeline prioritization and program selection.Assess emerging technologies, therapeutic targets, biomarkers, and clinical opportunities.Contribute to scientific publications, presentations, investigator engagement, and external medical communications.6. Executive LeadershipServe as a key member of the company's executive leadership team.Provide the CEO and Board with informed medical, clinical, and development recommendations.Contribute to corporate strategy, portfolio decisions, risk assessment, and organizational planning.Build and mentor high-performing clinical and medical teams as the organization grows.Qualifications & Experience:MD/MBBS or equivalent medical qualification is required.Advanced qualification in a relevant specialty is highly preferred.Typically 12–15+ years of experience in clinical development, medical affairs, translational medicine, pharmaceutical, biotechnology, or related fields.Significant experience in senior medical/clinical leadership roles within biotech or pharmaceutical organizations.Proven experience in clinical development and drug development programs.Experience working across preclinical-to-clinical translation is strongly preferred.Experience with RNA therapeutics, antisense oligonucleotides, gene-targeted therapies, rare diseases, precision medicine, or molecular therapeutics will be an advantage.Strong understanding of GCP, clinical trial methodology, pharmacovigilance, regulatory requirements, and drug development processes.Key Competencies:Clinical & Medical Leadership Translational Medicine Drug Development Strategy RNA & Gene-Targeted Therapeutics Clinical Trial Strategy Patient Safety & Benefit-Risk Assessment Regulatory & Health Authority Engagement KOL & Scientific Engagement Medical Affairs Precision Medicine Strategic Decision-Making Executive Leadership Team Building Scientific Communication Stakeholder Management