Clinical Research Associate
Upsilon Global · France
Tailor my CV for this job — freeSenior Clinical Research Associate (SCRA) – Oncology | France | PermanentUpsilon Global is supporting the growth of an established international medical-device organisation with an expanding clinical research portfolio and a strong focus on Oncology.We are seeking an experienced Senior Clinical Research Associate (SCRA) to join a well-rounded, collaborative clinical operations team in France, supporting the delivery of clinical studies across France and internationally.This opportunity is suited to an experienced clinical research professional who can independently oversee clinical trial sites, maintain high standards of data quality and regulatory compliance, and work closely with international study teams. The role offers the opportunity to contribute to Oncology-focused clinical research while taking ownership of monitoring activities within a growing medical-device organisation.Working alongside experienced clinical research professionals and cross-functional stakeholders, the successful candidate will play an important role in driving site performance, identifying and mitigating study risks, and supporting the successful delivery of clinical trials throughout the study lifecycle.POSITION DETAILSPosition: Senior Clinical Research Associate (SCRA)Therapeutic Focus: Oncology
The SCRA will take responsibility for site oversight, monitoring quality and compliance, ensuring that clinical trial activities are conducted in accordance with study protocols, applicable regulations and ICH-GCP requirements.The role encompasses the full clinical trial lifecycle, from study start-up through to close-out, with close engagement with investigators, site staff, sponsors and internal clinical operations teams.For a Senior CRA seeking greater ownership, broader project exposure and the opportunity to contribute to clinical research within an international medical-device environment, this position offers a compelling next step.KEY REQUIREMENTS:Strong experience working as a Clinical Research Associate, with demonstrated capability at Senior CRA level.Proven experience conducting independent clinical trial monitoring visits.Experience with interventional clinical trials, ideally within Oncology.Strong knowledge of ICH-GCP, applicable clinical trial regulations and monitoring practices.Experience across the clinical trial lifecycle, from study start-up through to close-out.Experience conducting Site Selection Visits, Site Initiation Visits, Interim Monitoring Visits and Close-Out Visits.Strong understanding of Source Data Verification (SDV) and Source Data Review (SDR).Experience managing site relationships and working with investigators, study coordinators and clinical trial sites.Ability to identify, assess and follow up on site-level risks, protocol deviations and compliance issues.Strong organisational, time-management and problem-solving skills.Excellent attention to detail and a commitment to clinical quality and patient safety.Ability to manage monitoring responsibilities independently while contributing effectively to an international study team.Strong written and verbal communication skills in French and English.Willingness and ability to travel regularly within France, with occasional international travel.KEY RESPONSIBILITIES:The successful candidate will be responsible for:Independently conducting Site Selection Visits, Site Initiation Visits, Interim Monitoring Visits and Close-Out Visits.Monitoring clinical trial sites in accordance with study protocols, sponsor requirements, ICH-GCP and applicable regulations.Conducting Source Data Verification and Source Data Review to ensure data quality, accuracy and integrity.Reviewing informed consent documentation and supporting patient safety and participant protection.Identifying, documenting and following up on protocol deviations, site issues and study-related risks.Providing guidance to investigators and site staff regarding study requirements, procedures and compliance expectations.Maintaining effective communication with investigators, study coordinators, sponsors and internal clinical operations teams.Preparing accurate, high-quality monitoring reports within required timelines.Ensuring essential regulatory and study documentation is complete, accurate and inspection-ready.Supporting risk-based monitoring activities and maintaining oversight of site performance and study quality.Contributing to study start-up, recruitment, ongoing study maintenance and close-out activities.Monitoring site progress and ensuring outstanding actions are followed up and resolved within agreed timelines.Reviewing Case Report Forms (CRFs), Investigator Site Files and other essential study documentation.Supporting regulatory submissions and approvals where required.Assisting with the resolution of audit findings and the implementation of corrective and preventive actions.Ensuring adverse events and serious adverse events are appropriately documented, reported and followed up in accordance with study requirements.Supporting the reconciliation and close-out of study materials, documentation and site activities.Escalating significant compliance concerns, risks and operational issues to the relevant study stakeholders.SYSTEMS AND TECHNICAL EXPERIENCE:Experience with clinical research systems and software would be beneficial, including:VeevaOracleMedidata RaveClinical Trial Management Systems (CTMS)Electronic Trial Master File (eTMF) systemsMicrosoft Word, Excel and PowerPointMicrosoft ProjectThe successful candidate should be comfortable working with clinical research systems, maintaining accurate documentation and meeting reporting requirements within established timelines.ADDITIONAL SKILLS:We are looking for a professional who demonstrates:Strong interpersonal and relationship-building capabilities.Confidence in independently managing clinical trial sites and monitoring activities.Effective communication with investigators, site teams and international stakeholders.The ability to manage multiple priorities and competing deadlines.Sound problem-solving, decision-making and risk-management skills.A proactive approach to site management, issue resolution and quality improvement.High attention to detail and a strong commitment to compliance.The ability to build productive relationships with investigators and site staff.A collaborative approach to working across different countries, cultures and functions.Flexibility and adaptability within a growing clinical research environment.A client-focused mindset and commitment to delivering high-quality work within agreed timelines.WHY CONSIDER THIS OPPORTUNITY?Joining a growing international medical-device organisation offers the opportunity to take on a senior monitoring role within a collaborative clinical research environment.Key benefits include:Oncology-focused clinical research: Contribute to clinical studies within a specialised therapeutic area.Collaborative international team: Work alongside experienced clinical research professionals and cross-functional stakeholders.Senior-level ownership: Independently manage site monitoring activities and contribute to study delivery and quality.Broader organisational exposure: Gain insight into clinical operations, medical-device development and international study execution.Meaningful stakeholder engagement: Build strong working relationships with investigators, internal teams and senior stakeholders.Professional development: Further develop your monitoring expertise within an expanding clinical research portfolio.Permanent employment: Build long-term experience within an established international organisation.INTERESTED IN DISCUSSING THE OPPORTUNITY?If you are an experienced Senior Clinical Research Associate with strong independent monitoring experience, proficiency in French and English, and an interest in Oncology-focused clinical research, we would welcome the opportunity to speak with you.Please apply directly through the LinkedIn advert or contact Upsilon Global on +44 203 875 9966 for a confidential discussion about the position.Upsilon Global connects clinical research professionals with opportunities across the clinical development sector.