Clinical Research Physician

The OpportunityThis role offers an exciting opportunity to contribute directly to the advancement of medical science through the delivery of clinical trials. Working closely with the Principal Investigator and multidisciplinary research team, you will provide medical oversight, participant care, safety monitoring, and clinical assessments while ensuring compliance with ICH-GCP, MHRA, GDPR, and study protocol requirements.Depending on experience and study allocation, successful candidates may also perform psychometric and clinical rating assessments for CNS and mental health research studies. Key ResponsibilitiesClinical Trial DeliverySupport the Principal Investigator in the safe and compliant conduct of clinical trials.Conduct participant screening, eligibility reviews, informed consent discussions, and clinical assessments.Perform physical examinations, medication reviews, diagnostic evaluations, and safety assessments.Review and sign study-related medical documentation and electronic data records.Participate in study visits, monitoring visits, audits, and sponsor reviews.Ensure participant welfare and provide appropriate medical care throughout study participation.Participant Safety & Medical OversightAssess and monitor participant safety throughout trial involvement.Evaluate and document adverse events, serious adverse events, and other safety findings.Support timely reporting of safety information to Sponsors and regulatory authorities.Collaborate with clinical teams to address participant safety concerns and protocol-related medical decisions.Research Governance & ComplianceConduct clinical research in accordance with approved study protocols, ICH-GCP, MHRA regulations, GDPR, and site SOPs.Maintain accurate, complete, and secure trial documentation.Support implementation of protocol amendments and participant re-consenting activities.Participate in investigator meetings, sponsor interactions, and study reviews.Clinical Rating & Assessments (Preferred)Conduct psychometric and clinical outcome assessments for CNS and mental health studies.Administer and score validated rating scales such as MADRS, CGI-S, GAD, MINI, and C-SSRS where applicable.Ensure consistency and reliability of participant assessments.Leadership & CollaborationWork collaboratively with Research Nurses, Study Coordinators, Principal Investigators, and Sponsors.Mentor junior clinicians and contribute to clinical research workforce development initiatives.Promote a culture of quality, participant safety, and continuous improvement.What We're Looking ForEssential✅ GMC Registration with a full licence to practise ✅ Post-registration clinical experience ✅ Previous clinical research experience as a Sub-Investigator, Principal Investigator, or equivalent research role ✅ Strong understanding of ICH-GCP and clinical trial regulations ✅ Excellent communication and interpersonal skills ✅ Ability to work independently and within multidisciplinary teams ✅ Strong attention to detail and organisational skills ✅ Commitment to participant safety and research excellenceDesirable⭐ Experience conducting psychometric and neurological assessments ⭐ CNS, Psychiatry, Neurology, Internal Medicine, or Primary Care experience ⭐ Membership of the Royal College of Physicians or equivalent specialist body ⭐ Current GCP certification ⭐ Experience mentoring clinical staff and research teams