PHARMACEUTICAL ORAL SOLID DOSAGE PROCESS SCIENTIST

PHARMACEUTICAL ORAL SOLID DOSAGE PROCESS SCIENTISTLocation: Jeddah, Saudi ArabiaEmployment type: Full-timeWorkplace: On-siteIndicative salary: SAR 17,000–26,000 per month𝐇𝐈𝐆𝐇𝐋𝐘 𝐓𝐄𝐂𝐇𝐍𝐈𝐂𝐀𝐋 𝐎𝐑𝐀𝐋 𝐒𝐎𝐋𝐈𝐃 𝐃𝐎𝐒𝐀𝐆𝐄 𝐑𝐎𝐋𝐄Candidates should have substantial hands-on experience with tablet, capsule or oral-solid manufacturing processes, preferably including granulation, blending, milling, compression, coating or process troubleshooting.This is not a general QA, regulatory or commercial position.We are looking for a pharmaceutical scientist or engineer who understands how material properties, formulation parameters, equipment settings and manufacturing conditions interact throughout the oral-solid production process.𝐀𝐛𝐨𝐮𝐭 𝐭𝐡𝐞 𝐫𝐨𝐥𝐞Palomba General Trading LLC is looking for a Pharmaceutical Oral Solid Dosage Process Scientist to support technically demanding pharmaceutical manufacturing projects in Saudi Arabia and the wider GCC.The role will focus on the industrial processing of tablets, capsules, powders and granules, with particular attention to process robustness, equipment performance and troubleshooting.The successful candidate will work across formulation, manufacturing, engineering and technical project teams to improve product consistency and manufacturing performance.The role may involve both existing production lines and new manufacturing projects.𝐊𝐞𝐲 𝐓𝐞𝐜𝐡𝐧𝐢𝐜𝐚𝐥 𝐑𝐞𝐬𝐩𝐨𝐧𝐬𝐢𝐛𝐢𝐥𝐢𝐭𝐢𝐞𝐬

• Evaluate oral-solid manufacturing processes from raw-material preparation through finished dosage form.
• Support optimisation of powder blending.
• Evaluate granulation processes.
• Review wet and dry granulation parameters.
• Support milling and particle-size-control activities.
• Analyse powder flow and blend uniformity.
• Review lubricant addition and final blending.
• Support tablet-compression optimisation.
• Analyse compression-force requirements.
• Investigate tablet-weight variability.
• Evaluate hardness and friability issues.
• Support capsule-filling processes where applicable.
• Review coating-process parameters.
• Support troubleshooting of coating defects.
• Evaluate process yield and product loss.
• Investigate segregation during transfer.
• Analyse batch-to-batch variability.
• Support scale-up and process-transfer activities.
• Review process parameters during pilot and commercial batches.
• Support manufacturing trials.
• Participate in root-cause investigations.
• Work with engineering teams where equipment performance contributes to manufacturing problems.𝐏𝐨𝐰𝐝𝐞𝐫 & 𝐆𝐫𝐚𝐧𝐮𝐥𝐚𝐭𝐢𝐨𝐧 𝐒𝐜𝐢𝐞𝐧𝐜𝐞Candidates should understand parameters such as:
• Particle-size distribution
• Bulk density
• Tapped density
• Flowability
• Compressibility
• Moisture content
• Granule strength
• Binder concentration
• Liquid addition rate
• Mixing time
• Impeller speed
• Chopper speed
• Endpoint determination
• Drying conditions
• Final moisture𝐁𝐥𝐞𝐧𝐝𝐢𝐧𝐠 & 𝐂𝐨𝐧𝐭𝐞𝐧𝐭 𝐔𝐧𝐢𝐟𝐨𝐫𝐦𝐢𝐭𝐲The role may include:
• Blend-time optimisation
• Low-dose API distribution
• Segregation-risk assessment
• Excipient distribution
• Lubrication optimisation
• Sampling strategies
• Blend-uniformity troubleshooting
• Powder-transfer assessment𝐓𝐚𝐛𝐥𝐞𝐭 𝐂𝐨𝐦𝐩𝐫𝐞𝐬𝐬𝐢𝐨𝐧Relevant parameters may include:
• Compression force
• Pre-compression
• Main compression
• Turret speed
• Fill depth
• Tablet weight
• Hardness
• Thickness
• Friability
• Disintegration
• Ejection forceCandidates should be capable of investigating manufacturing defects such as:
• Capping
• Lamination
• Sticking
• Picking
• Weight variation
• Excessive friability
• Poor hardness
• Slow disintegration𝐂𝐨𝐚𝐭𝐢𝐧𝐠 𝐏𝐫𝐨𝐜𝐞𝐬𝐬𝐞𝐬Experience may include:
• Film coating
• Functional coating
• Enteric coating
• Spray-rate optimisation
• Atomisation
• Inlet-air temperature
• Exhaust temperature
• Bed temperature
• Pan speed
• Drying conditionsThe candidate may troubleshoot:
• mottling;
• roughness;
• peeling;
• twinning;
• sticking;
• uneven coating;
• colour variation.𝐂𝐚𝐩𝐬𝐮𝐥𝐞 𝐀𝐩𝐩𝐥𝐢𝐜𝐚𝐭𝐢𝐨𝐧𝐬Relevant experience may include:
• Powder filling
• Granule filling
• Fill-weight control
• Flow problems
• Dosing-disc systems
• Tamping systems
• Capsule closing
• In-process controls𝐏𝐫𝐨𝐜𝐞𝐬𝐬 𝐄𝐪𝐮𝐢𝐩𝐦𝐞𝐧𝐭Candidates may have worked with:
• High-shear granulators
• Fluid-bed processors
• Roller compactors
• Mills
• Sieves
• Bin blenders
• V-blenders
• IBC systems
• Tablet presses
• Capsule fillers
• Coating pans
• Vacuum-transfer systems
• Contained powder-transfer systems𝐓𝐫𝐨𝐮𝐛𝐥𝐞𝐬𝐡𝐨𝐨𝐭𝐢𝐧𝐠The scientist should be capable of distinguishing between problems originating from:
• formulation;
• raw materials;
• particle characteristics;
• process parameters;
• equipment configuration;
• environmental conditions;
• material transfer.The goal is not merely to document a manufacturing deviation, but to identify the most credible technical cause and define a practical corrective approach.𝐂𝐫𝐢𝐭𝐢𝐜𝐚𝐥 𝐏𝐫𝐨𝐜𝐞𝐬𝐬 𝐏𝐚𝐫𝐚𝐦𝐞𝐭𝐞𝐫𝐬Candidates should be comfortable working with:
• Mixing time
• Granulation endpoint
• Moisture
• Drying temperature
• Milling speed
• Screen size
• Blend time
• Compression force
• Tablet-press speed
• Coating spray rate
• Airflow
• Temperature
• Product yield𝐂𝐚𝐧𝐝𝐢𝐝𝐚𝐭𝐞 𝐏𝐫𝐨𝐟𝐢𝐥𝐞The ideal candidate is a pharmaceutical scientist or process engineer with strong practical oral-solid manufacturing experience.We are particularly interested in candidates capable of moving comfortably between:
• formulation science;
• powder technology;
• manufacturing operations;
• equipment performance;
• process data;
• troubleshooting.The candidate should be able to look at a tablet-production problem and determine whether the issue is likely to originate from the powder, formulation, process or machine.𝐑𝐞𝐪𝐮𝐢𝐫𝐞𝐦𝐞𝐧𝐭𝐬Bachelor’s or Master’s degree in:
• Pharmaceutical Sciences
• Pharmacy
• Pharmaceutical Technology
• Chemical Engineering
• Process Engineering
• Chemistry
• or a closely related discipline.Minimum 5 years of relevant oral-solid pharmaceutical manufacturing or process-development experience preferred.Hands-on experience with tablet or capsule manufacturing required.Experience with granulation, blending or compression required.Strong understanding of powder behaviour.Experience troubleshooting manufacturing problems.Practical knowledge of GMP manufacturing environments.Ability to interpret manufacturing and process data.Experience with process scale-up or technology transfer desirable.Excellent written and spoken English.Arabic is considered an advantage.𝐏𝐫𝐞𝐟𝐞𝐫𝐫𝐞𝐝 𝐓𝐞𝐜𝐡𝐧𝐢𝐜𝐚𝐥 𝐄𝐱𝐩𝐨𝐬𝐮𝐫𝐞
• Oral Solid Dosage
• Tablet Manufacturing
• Granulation
• Powder Processing
• Tablet Compression
• Capsule Manufacturing
• Pharmaceutical Manufacturing
• Process Development
• Film Coating
• GMP
• Process Scale-Up
• Troubleshooting𝐏𝐫𝐞𝐟𝐞𝐫𝐫𝐞𝐝 𝐈𝐧𝐝𝐮𝐬𝐭𝐫𝐲 𝐄𝐱𝐩𝐞𝐫𝐢𝐞𝐧𝐜𝐞
• Pharmaceutical manufacturing
• Generic pharmaceuticals
• CDMO manufacturing
• Nutraceutical manufacturing
• Tablet production
• Capsule production
• Pharmaceutical process equipment𝐖𝐡𝐚𝐭 𝐰𝐞 𝐨𝐟𝐟𝐞𝐫Full-time position based in Jeddah, Saudi Arabia.Indicative salary: SAR 17,000–26,000 per month, depending on experience and technical qualifications.Performance-related incentives may apply.Health insurance.Opportunity to participate in technically demanding pharmaceutical manufacturing projects across Saudi Arabia and the wider GCC.Exposure to international pharmaceutical process-equipment manufacturers and specialist technology partners.Direct involvement in manufacturing optimisation, troubleshooting, process scale-up and equipment-related projects.International technical environment connecting pharmaceutical manufacturers with specialised engineering and technology partners.𝐀𝐛𝐨𝐮𝐭 𝐏𝐚𝐥𝐨𝐦𝐛𝐚 𝐆𝐞𝐧𝐞𝐫𝐚𝐥 𝐓𝐫𝐚𝐝𝐢𝐧𝐠 𝐋𝐋𝐂Palomba General Trading LLC is a Dubai-based international trading and business development company operating between the Middle East and Europe.The company develops technical and commercial cooperation with specialised manufacturers and industrial customers across pharmaceutical, nutraceutical, food, cosmetics, specialty ingredients and industrial process technologies.Palomba General Trading supports qualified customer projects through technical coordination, application development and international market development.