PHARMACEUTICAL TECHNOLOGY TRANSFER & SCALE-UP SCIENTIST

PHARMACEUTICAL TECHNOLOGY TRANSFER & SCALE-UP SCIENTISTLocation: Riyadh, Saudi ArabiaEmployment type: Full-timeWorkplace: On-siteIndicative salary: SAR 18,000–27,000 per month𝐇𝐈𝐆𝐇𝐋𝐘 𝐓𝐄𝐂𝐇𝐍𝐈𝐂𝐀𝐋 𝐏𝐇𝐀𝐑𝐌𝐀𝐂𝐄𝐔𝐓𝐈𝐂𝐀𝐋 𝐓𝐄𝐂𝐇𝐍𝐎𝐋𝐎𝐆𝐘 𝐓𝐑𝐀𝐍𝐒𝐅𝐄𝐑 & 𝐒𝐂𝐀𝐋𝐄-𝐔𝐏 𝐑𝐎𝐋𝐄Candidates should have practical experience transferring pharmaceutical products from R&D or pilot scale into commercial manufacturing.Experience with formulation scale-up, manufacturing-process optimisation, technical transfer documentation, batch troubleshooting and cross-functional coordination is essential.This is not a general quality-assurance, regulatory or commercial position.𝐀𝐛𝐨𝐮𝐭 𝐭𝐡𝐞 𝐫𝐨𝐥𝐞Palomba General Trading LLC is looking for a Pharmaceutical Technology Transfer & Scale-Up Scientist to support pharmaceutical and nutraceutical manufacturing projects across Saudi Arabia and the wider GCC.The role will focus on converting laboratory and pilot formulations into robust industrial manufacturing processes.The successful candidate will work across R&D, production, engineering, quality and equipment teams to ensure that formulations can be reproduced consistently at manufacturing scale.The role is particularly relevant to:

• oral liquids;
• suspensions;
• powders;
• granules;
• semisolids;
• nutraceutical products;
• selected oral-solid preparation processes.𝐊𝐞𝐲 𝐓𝐞𝐜𝐡𝐧𝐢𝐜𝐚𝐥 𝐑𝐞𝐬𝐩𝐨𝐧𝐬𝐢𝐛𝐢𝐥𝐢𝐭𝐢𝐞𝐬
• Transfer formulations and manufacturing processes from development scale to production scale.
• Evaluate scale-dependent process risks.
• Define critical process parameters.
• Support identification of critical material attributes.
• Compare laboratory, pilot and commercial-scale process behaviour.
• Develop scale-up strategies.
• Review batch size and equipment-capacity implications.
• Optimise ingredient-addition sequences.
• Evaluate mixing and blending conditions.
• Review shear requirements.
• Assess heating and cooling requirements.
• Evaluate powder incorporation and hydration behaviour.
• Support granulation and drying parameters where relevant.
• Evaluate homogenisation requirements.
• Support process-time optimisation.
• Investigate manufacturing deviations related to formulation or process conditions.
• Troubleshoot scale-up failures.
• Support pilot batches.
• Support engineering and exhibit batches where applicable.
• Participate in commercialisation activities.
• Coordinate transfer activities between R&D and manufacturing teams.
• Prepare and review technology-transfer documentation.
• Support process-risk assessments.
• Assist in defining equipment requirements.
• Participate in manufacturing trials.
• Review batch records and manufacturing instructions.
• Support process-validation readiness.𝐓𝐞𝐜𝐡𝐧𝐨𝐥𝐨𝐠𝐲 𝐓𝐫𝐚𝐧𝐬𝐟𝐞𝐫 𝐀𝐫𝐞𝐚𝐬Candidates may work on:
• R&D to pilot transfer
• Pilot to commercial transfer
• Site-to-site technology transfer
• Product localisation
• Manufacturing-process adaptation
• New equipment introduction
• Process optimisation
• Capacity expansion
• Production troubleshooting𝐏𝐫𝐨𝐜𝐞𝐬𝐬 𝐏𝐚𝐫𝐚𝐦𝐞𝐭𝐞𝐫𝐬The scientist should be comfortable evaluating:
• Batch size
• Mixing time
• Agitation speed
• Shear
• Temperature
• Heating rate
• Cooling rate
• Addition sequence
• Hydration time
• Homogenisation conditions
• Hold time
• Vacuum
• Drying conditions
• Moisture
• Particle size
• Blend uniformity
• Viscosity
• pH
• Yield𝐃𝐨𝐬𝐚𝐠𝐞 𝐅𝐨𝐫𝐦𝐬Relevant experience may include:
• Oral solutions
• Syrups
• Suspensions
• Emulsions
• Drops
• Creams
• Gels
• Ointments
• Powders
• Granules
• Sachets
• Nutraceutical products
• Oral-solid intermediates𝐄𝐪𝐮𝐢𝐩𝐦𝐞𝐧𝐭 𝐄𝐱𝐩𝐨𝐬𝐮𝐫𝐞Candidates may have experience with:
• Mixing vessels
• High-shear mixers
• Homogenisers
• Powder blenders
• Mills
• Granulators
• Dryers
• Vacuum systems
• Dosing systems
• Transfer systems
• Process skids
• Filling interfaces𝐓𝐫𝐨𝐮𝐛𝐥𝐞𝐬𝐡𝐨𝐨𝐭𝐢𝐧𝐠The candidate should be capable of investigating issues such as:
• inconsistent viscosity;
• poor blend uniformity;
• sedimentation;
• phase separation;
• excessive processing time;
• temperature-control problems;
• scale-related mixing failure;
• powder agglomeration;
• poor dissolution;
• yield loss;
• batch-to-batch variability.𝐃𝐨𝐜𝐮𝐦𝐞𝐧𝐭𝐚𝐭𝐢𝐨𝐧Relevant experience may include:
• Technology-transfer protocols
• Manufacturing instructions
• Master batch records
• Process flow diagrams
• P&IDs
• Risk assessments
• Critical parameter assessments
• Batch comparison reports
• Deviation investigations
• Process-development reports
• Validation-support documentation𝐂𝐚𝐧𝐝𝐢𝐝𝐚𝐭𝐞 𝐏𝐫𝐨𝐟𝐢𝐥𝐞We are looking for a scientist or engineer who understands that a formulation working in a five-litre laboratory vessel does not magically remain identical when somebody makes five thousand litres of it. Physics, as usual, insists on participating.The ideal candidate should understand the relationship between:
• formulation composition;
• raw-material behaviour;
• equipment geometry;
• shear;
• heat transfer;
• mixing;
• batch size;
• processing time.Candidates should be able to distinguish whether a manufacturing problem originates from the formula, the process, the equipment or the interaction between them.𝐑𝐞𝐪𝐮𝐢𝐫𝐞𝐦𝐞𝐧𝐭𝐬Bachelor’s or Master’s degree in:
• Pharmaceutical Sciences
• Pharmacy
• Pharmaceutical Technology
• Chemical Engineering
• Process Engineering
• Chemistry
• or another closely related discipline.Minimum 5 years of relevant pharmaceutical process-development, technology-transfer or scale-up experience preferred.Hands-on experience transferring products into manufacturing.Strong understanding of pharmaceutical formulation and process development.Experience supporting pilot or commercial manufacturing batches.Ability to analyse process parameters and manufacturing data.Experience troubleshooting industrial batches.Understanding of GMP manufacturing environments.Ability to work with R&D, production, engineering and quality teams.Excellent written and spoken English.Arabic is considered an advantage but is not mandatory.𝐏𝐫𝐞𝐟𝐞𝐫𝐫𝐞𝐝 𝐓𝐞𝐜𝐡𝐧𝐢𝐜𝐚𝐥 𝐄𝐱𝐩𝐨𝐬𝐮𝐫𝐞
• Technology Transfer
• Process Scale-Up
• Pharmaceutical Manufacturing
• Formulation Development
• Process Development
• GMP
• Manufacturing Science
• Process Optimisation
• Troubleshooting
• Process Validation
• Mixing
• Powder Processing𝐏𝐫𝐞𝐟𝐞𝐫𝐫𝐞𝐝 𝐈𝐧𝐝𝐮𝐬𝐭𝐫𝐲 𝐄𝐱𝐩𝐞𝐫𝐢𝐞𝐧𝐜𝐞
• Pharmaceutical manufacturing
• Nutraceutical manufacturing
• CDMO environments
• Generic pharmaceuticals
• Consumer healthcare
• Oral liquids
• Semisolids
• Powder processing𝐖𝐡𝐚𝐭 𝐰𝐞 𝐨𝐟𝐟𝐞𝐫Full-time position based in Riyadh, Saudi Arabia.Indicative salary: SAR 18,000–27,000 per month, depending on technical experience and qualifications.Performance-related incentives may apply where relevant.Health insurance.Exposure to pharmaceutical manufacturers and international process-technology partners.Opportunity to participate in technically demanding pharmaceutical manufacturing and localisation projects across Saudi Arabia and GCC markets.Direct involvement in projects from formulation and pilot development through industrial manufacturing.International working environment connecting pharmaceutical companies, technical specialists and equipment manufacturers.𝐀𝐛𝐨𝐮𝐭 𝐏𝐚𝐥𝐨𝐦𝐛𝐚 𝐆𝐞𝐧𝐞𝐫𝐚𝐥 𝐓𝐫𝐚𝐝𝐢𝐧𝐠 𝐋𝐋𝐂Palomba General Trading LLC is a Dubai-based international trading and business development company operating between the Middle East and Europe.The company develops technical and commercial cooperation with specialised manufacturers and industrial customers across pharmaceutical, nutraceutical, food, cosmetics, specialty ingredients and industrial process technologies.Palomba General Trading supports qualified customer projects through technical coordination, application development and international market development.