Principal Scientist, Cancer Vaccines

ICR's Cancer Prevention science centers on developing preventive cancer vaccines. We are hiring a Principal Scientist with a deep background in peptide-based vaccine development, cancer immunology and immuno-oncology. As part of our mission to prevent age-related disease, training human immune systems to spot and destroy cancer before it becomes a problem is critical. We truly believe that an ounce of prevention is worth a pound of cure.With us, you'll get to:Lead ICR's Cancer Prevention Group in researching and developing novel preventive cancer vaccinesDrive end-to-end design, execution and interpretation of preclinical vaccine studies, directly shaping the path to human translationCollaborate closely external KOLs and CRO partners to turn cutting-edge cancer immunology insights into first-in-class preventive vaccine programsPlease apply if you have:A PhD, MD or both and at least 10 years of vaccine development experience, preferably cancer vaccinesIn-depth knowledge of and experience researching personalized cancer vaccines, including peptide-based vaccines and neoantigen-based cancer vaccinesExtensive experience with vaccine epitope identification, selection/prioritization (of neoantigens), vaccine adjuvants and immune response monitoringExperience with molecular T cell receptor repertoire analysis and tracking, T cell proliferation assays, cytokine release assays and ELISPOTExperience deriving antigen-specific T cell clones and linesExpertise in cancer stem cell antigens, tumor-associated antigens, neoantigens, immuno-editing and immuno-monitoringExtensive knowledge of and experience with vaccine delivery systems, including peptide-, cell- and viral-based systemsThe ability to work well with CROs and manage external projectsEven if you don't meet all of these criteria, please apply anywayAnd you'll need:An easygoing, friendly personalityThe ability to work in the United States without sponsorshipIf you don't combine your cover letter with your CV or resume when you apply through LinkedIn, after you apply please send your cover letter only to: apply@invitroresearch.com with "Cover [Your name]" as the Subject line.Position title and salary are commensurate with experience.The compensation ranges listed below are starting ranges.Starting base pay range: $165,000/yr - $215,000/yrStarting bonus range: $7,500/yr - $20,000/yrWhy join ICR?EXERCISE your intellect in challenging and rewarding scienceENTER an career dedicated to a mission that matters to everyoneENGAGE in cutting-edge regenerative medicine researchEXCELLENT research environment, salaries and relocation expenses (fully covered!)