Scientist

Russell Tobin is partnering with a top biotech/pharmaceutical organization to identify a Scientist for an opportunity near South San Francisco, CA.

Responsibilities

Execute and optimize research-scale lentiviral vector production, including production capacity improvements and transition to suspension culture. Produce and characterize research-grade lentiviral vectors for in vitro evaluation and preclinical research support. Develop, optimize, and perform molecular and cell-based assays to assess vector quality, titer, gene delivery, CAR expression, and functional activity. Perform aseptic mammalian cell culture and primary human immune cell engineering, preferably T cells. Utilize flow cytometry to evaluate transduction efficiency, CAR expression, and cell phenotype. Independently design experiments, troubleshoot technical challenges, analyze results, and communicate findings to project teams. Maintain accurate electronic laboratory records and support laboratory operations, equipment maintenance, and safety requirements.

Requirements

BS/MS with 5+ years of industry experience or PhD in Immunology, Virology, Molecular Biology, Bioengineering, Cell Biology, or a related discipline. Hands-on experience with lentiviral vector production and characterization. Strong proficiency in aseptic mammalian cell culture and experience with primary human immune cells, preferably T cells. Experience developing, optimizing, and troubleshooting molecular or cell-based analytical assays. Technical proficiency in flow cytometry and at least one quantitative molecular assay platform, such as qPCR or ddPCR.

Preferred Qualifications

3+ years of relevant post-graduate research experience in biotechnology, pharmaceutical research, or academia. Experience with gene delivery vectors for in vivo CAR T or related preclinical research programs. Experience with suspension-based lentiviral vector production, scale-up, or process development. Familiarity with CAR T-cell functional assays, multiparameter flow cytometry, nonviral delivery platforms, genome engineering, or next-generation sequencing. Experience with automation, liquid handling, and high-throughput analytical workflows. Proficiency with FlowJo, GraphPad Prism, and Benchling. Additional Details:Location model: South San Francisco, CA (Onsite)Shift: Mon to Fri 9am to 5pm PSTPosition Type: 12-month contract (potential to extend)Pay range approved: $50/hr - $63.50/hr (depending on experience) APPLY NOW! Russell Tobin is a professional recruitment and staffing advisory firm that connects job seekers and employers across various industries. We are a staffing arm of Pride Global. Affiliates include Russell Tobin, Pride health, Pride Now and Pride One.#RTA#JD-SCIENCEFor workers in the United States, PrideGlobal and it's affiliates offers eligible employee’s comprehensive healthcare coverage (medical, dental, and vision plans), supplemental coverage (accident insurance, critical illness insurance and hospital indemnity), 401(k)-retirement savings, life & disability insurance, an employee assistance program, legal support, pet insurance and employee discounts with preferred vendors.Equal Employment OpportunityPrideGlobal and it's affiliates are an equal opportunity employer. We do not discriminate on the basis of the race, religious creed, color, national origin, ancestry, physical disability, mental disability, reproductive health decision making, medical condition, genetic information, marital status, sex, gender, gender identity, gender expression, age, sexual orientation, veteran or military status, or any other characteristic protected by applicable federal, state, or local law.Fair Chance EmploymentPrideGlobal and it's affiliates are a Fair Chance employer. We consider all qualified applicants, including those with criminal histories, in a manner consistent with applicable state and local Fair Chance laws and ordinances, including, the California Fair Chance Act and all applicable local Fair Chance ordinances.AccommodationsWe are committed to providing reasonable accommodations to applicants and employees with disabilities. If you require a reasonable accommodation to participate in the application or interview process, or to perform the essential functions of this role, please contact us.Only applicable for San Francisco Candidates: Under the San Francisco Lactation in the Workplace Ordinance, we will provide written notice of lactation accommodation rights, and this notice will automatically be given upon hiring, any inquiry of parental leave or lactation accommodation.Only applicable for Kentucky positions: For this type of employment, state law requires a criminal record check as a condition of employment. This applies to direct care staff (Examples: RN, LPN, Nurse Aides, Therapists) referred to Kentucky nursing facilities, assisted living communities, or long-term care facilities, in accordance with KRS 216.793.