Scientist III - LC/MS (Bioanalytical)

At BioAgilytix, we are passionate about premier science and the impact it has on our world. Our team of highly experienced scientists and professionals deliver tailored services for supporting new medicine breakthroughs with best-in-class bioanalytical services. We are tirelessly committed to our customers by being solution-oriented and deadline-driven. . . and we are growing. Our culture is fast-paced, fun and never boring. Because we work across numerous clients and drug modalities, your career can develop rapidly. You’ll gain experience with a variety of challenges all while you enable life-changing, life-saving therapeutics to the patients who need them.In this hands-on, laboratory-based Scientist role, you will design, develop, and execute bioanalytical methods and experiments supporting the advancement of new therapies, with a particular focus on large-molecule LC/MS applications. You’ll spend much of your time at the bench performing method development, optimization, and GxP-compliant validation; generating and analyzing data; evaluating assay performance; and conducting targeted and untargeted analyses using liquid chromatography and mass spectrometry.This role is a strong fit for someone who enjoys being in the lab, working through complex scientific problems, and seeing a method through from development to validation and execution. You’ll work across a variety of client programs and therapeutic areas, which means the science and day-to-day challenges can vary quite a bit. We’re looking for someone with strong LC/MS experience who is comfortable working in a regulated environment and understands the importance of producing accurate, high-quality data.Essential ResponsibilitiesLead assay development, validation, and sample analysis of biologics, proteins, peptides, ADCs, and/or biomarkers using chromatographic and mass spectrometric (LC/MS) techniques in support of preclinical, clinical, and product release studiesPlan and direct experimental design for junior staffDrive bioanalytical projects to align with client timelinesFrequent communication with clients to discuss technical details and provide project updatesAdvise clients on LC/MS assay best practicesAuthor documents (methods, SOPs, reports)Statistical analysis of bioanalytical dataReview of documentationPeer review raw dataPrepare reagentsTroubleshoot assaysDesign assay runs independentlyResponsible for prompt identification and notification of deviationsWrite plans/reports for sample analysisOrder and keep accurate inventories of supplies for laboratory needs and forecast future needs based on projected project needsPerform assays according to GLP guidance or SOPsAdditional ResponsibilitiesOther duties as neededMinimum Preferred Qualifications: SkillsExperience with development, validation and execution of chromatographic and mass spectrometric assays (LC/MS), and/or ability to perform most tasks associated with custom research planning and bench workMust work effectively within team to meet objectives under time constraintsAbility to take direction well and multi-taskDetail oriented and highly organizedDemonstrated expertise in chromatographic assay developmentAdvanced capabilities in data analysis, data visualization statistical analysisLC/MS assay development and validationMicrosoft word, Excel, Sciex OS/Analyst, MassLynx, Chromeleon, Watson LIMS, JMP, Graphpad PrismAbility to develop protein binding, CYP inhibition, CYP induction, or CYP phenotyping and/or ability to develop chromatographic assays using HPLC or LC/MS/MSExperience working in a GxP environment preferredExcellent oral and written communication skillsMinimum Preferred Qualifications: Education/Experience Bachelor’s degree in chemistry, biochemistry, biotechnology, biology, immunology, or related field with not less than 12 years’ experience in a scientific laboratory environment; orMaster’s degree in chemistry, biochemistry, biotechnology, biology, immunology, or related field with not less than ten (10) years’ experience in a scientific laboratory environment; orPhD in chemistry, biochemistry, biotechnology, biology, immunology, or related field with not less than eight (8) years’ experience in a scientific laboratory environmentDemonstrated expertise in developing chromatographic and mass spectrometric assays including LC/MS and LC/MS/MS for bioanalytical studies by extracting analytes of interest from complex biological matrices using protein precipitation, liquid-liquid, solid phase, immunoprecipitation or other extraction techniqueAdvanced capabilities in data analysis, data visualization statistical analysisSupervisory ResponsibilityThis position may supervise Analyst I/II/IIISupervision ReceivedInfrequent supervision and instructionsFrequently exercises discretionary authorityWorking EnvironmentPrimarily laboratory environmentExposure to biological fluids with potential exposure to infectious organismsRare exposure to skin and lung irritants, toxic materials, and hazardous wastePersonal protective equipment required, such as protective eyewear, garments, and glovesRoutinely uses standard office equipment such as computers, phones, photocopiers, and filing cabinetsPhysical DemandsAbility to work in an upright and/or stationary position for up to 8 hours per dayRepetitive hand movement of both hands with the ability to make fast, simple, repeated movements of the fingers, hands, and wrists to operate lab equipmentFrequent mobility neededFrequent crouching, stooping, with frequent bending and twisting of upper body and neckLight to moderate lifting and carrying (or otherwise moves) objects including laboratory equipment, laboratory supplies, and laptop computer with a maximum lift of 20 poundsAbility to access and use a variety of computer softwareAbility to communicate information and ideas so others will understand, with the ability to listen to and understand information and ideas presented through spoken words and sentencesFrequently interacts with others to obtain or relate information to diverse groupsRequires multiple periods of intense concentrationPerforms a wide range of variable tasks as dictated by variable demands and changing conditions with little predictability as to the occurrenceAbility to perform under stress and multi-taskRegular and consistent attendancePosition Type and Expected Hours of WorkThis is a full-time positionSome flexibility in hours is allowed, but the employee must be available during the “core” work hours as published in the BioAgilytix Employee HandbookOccasional weekend, holiday, and evening work requiredOccasional travel requiredBenefits And Other PerksMedical Insurance (HDHP with HSA; PPO), Dental Insurance, Vision Insurance, Flexible Spending Account (medical; dependent care), Short Term Disability | Long Term Disability Life Insurance, Paid Time Off (4 weeks per year), Parental Leave, Paid Holidays (9 scheduled; 5 floating), 401k with Employer Match, Employee Referral ProgramCOMMITMENT TO EQUAL OPPORTUNITYBioAgilytix provides equal employment opportunities to all employees and applicants for employment without regard to race, color, ancestry, national origin, gender, sexual orientation, marital status, religion, age, disability, gender identity, results of genetic testing, service in the military, or any other group protected by federal, state, or local law.To learn more about how we collect, use, and protect your information, please review our Privacy Policy and Terms of Use.We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses and identifying potential inconsistencies or verification signals in application materials based on available information. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.