Senior Scientist – Biomarker R&D (m/f/d)

Founded in May 2020, my client Noselab, based in Munich, Germany, focuses on a new, proprietary and groundbreaking platform for the detection, evaluation and characterization of molecular/protein biomarkers through the analysis of nasal fluid. This unique method is complemented by an innovative, data-driven medical approach that enables comprehensive biomarker profiling, improves the understanding of diseases and supports personalized treatment decisions.We are looking for an experienced Senior Scientist with a strong background in industrial biomarker research and development.Key responsibilities:Lead and execute biomarker discovery, characterization and validation projects, from experimental design through data analysis, interpretation and reporting.Design, optimize and apply bioanalytical methods for protein biomarker analysis including immunoassays, targeted and discovery-based proteomics, and other emerging technologies.Work with complex biological samples, develop robust sample preparation and pre- analytical workflows, and assess analytical performance, reproducibility and sources of variability.Drive the expansion of Noselab's biomarker platform beyond its current focus on proteins, evaluating the potential of complementary approaches such as other omics technologies, extracellular vesicle analysis and nucleic acid-based methods.Integrate and interpret data from different analytical platforms to identify promising biomarkers, evaluate their biological relevance, analytical robustness and support their translation into downstream applications.Drive internal R&D and collaborative projects with pharmaceutical, biotech and academic partners, ensuring scientific quality, timely execution and actionable deliverablesEvaluate new technologies, analytical platforms and biomarker candidates to expand Noselab's technological capabilities and biomarker portfolio.Communicate scientific results to internal and external stakeholders and contribute to publications, presentations, application notes, grant proposals, patent applications, project outlines and strategic R&D planning.Provide scientific guidance to colleagues and contribute to the development of efficient, high-quality workflows.

Key Requirements

PhD or equivalent qualification in Biochemistry, Molecular Biology, Biotechnology, Analytical Chemistry or a related life science discipline.Demonstrated experience in biomarker discovery and development within the pharmaceutical or biotechnology industry, with a track record of independently driving research projects and translating scientific findings into robust analytical or biological evidence.Strong expertise in protein biomarkers and bioanalytical methods, including assay development, optimization and validation.Experience in proteomics is a major advantage, particularly LC-MS-based proteomics, affinity-based proteomic platforms or the integration of discovery proteomics with targeted biomarker validation.Strong experimental design, quantitative data analysis and critical interpretation skills, including the ability to assess analytical performance, biological variability, confounders and the robustness of biomarker findings.Experience working with complex biological matrices, such as plasma, serum, CSF, tissue or other biofluids, and an understanding of pre-analytical variables.Ability to work independently, prioritize competing project demands and communicate scientific findings effectively in an interdisciplinary environment.Excellent written and spoken English.Experience with other omics technologies, extracellular vesicles, cfDNA or emerging biomarker modalities is a plus, as is the ability to assess the potential of new technologies and translate them into practical R&D applications.Preferred qualificationsExperience/background in the field of neurodegenerative diseases or another field of neuroscience is a strong plusExperience in working in regulated environments (e.g. GCLP) and adhering to standardsAdditional experience in nucleic acid analysis, genomics and liquid biopsies

What We Offer

Direct impact on how cutting-edge diagnostics accelerate biopharma innovation A dynamic, collaborative and purpose-driven work cultureA permanent full-time position with competitive salary and long-term career growth opportunitiesFlexible work setup with time on-site in Munich and home-office options