Senior Scientist, Oncology Drug Discovery

Position SummaryThe organization is seeking a skilled scientist to contribute deep expertise in MPN and oncology biology to the advancement of its drug discovery programs. The successful candidate will apply strong scientific judgment to inform experimental design, interpret complex datasets, and troubleshoot unexpected results, operating within a program strategy established by senior scientific leadership. The ideal candidate will possess substantive scientific knowledge of myeloproliferative neoplasms and driver-mutation biology, and will be seeking to deepen this expertise within a collaborative team environment rather than to determine overall program direction.Key ResponsibilitiesContribute scientific expertise to the design and interpretation of studies supporting target validation, mechanism-of-action understanding, and lead characterization, within the scientific direction established for MPN and related myeloid malignancy programsProvide scientific input on MPN-relevant model systems and study designs, including approaches involving primary patient samples and bone marrow biology, as directed by the broader program planContribute as an active member of cross-functional drug discovery teams, providing scientific input to colleagues in non-clinical sciences, DMPK, and translational science to inform subsequent decisionsPresent results and scientific updates to the immediate project team and research leadership on a regular basisMaintain thorough and accurate scientific records and data files in accordance with internal documentation standardsPrepare sections of scientific reports, presentations, and, where applicable, publications or patent filings, for review by program leadershipMonitor scientific literature and emerging methodologies relevant to assigned programs and bring promising developments to the attention of the teamRequired QualificationsPh.D. in Oncology, Cancer Biology, Hematology, Molecular Biology, Cell Biology, Pharmacology, or a related discipline, together with a minimum of two years of industry (biotechnology/pharmaceutical) drug discovery experience (postdoctoral experience will be considered); alternatively, a Master's degree in a related discipline with a minimum of six years of equivalent industry experienceSubstantive scientific knowledge of myeloproliferative neoplasms (e.g., polycythemia vera, essential thrombocythemia, myelofibrosis) or closely related myeloid malignancies, sufficient to inform study design and interpret complex dataDemonstrated capacity to contribute independently on a day-to-day basis, while operating within a strategy and set of priorities established by program leadershipExperience serving as a contributing member of a cross-functional drug discovery teamAbility to communicate scientific data and technical detail clearly to an immediate project teamPreferred QualificationsBackground in immunology, particularly as related to cancer immunotherapy or immune cell biologyKnowledge of biologics (e.g., antibodies, antibody-drug conjugates, bispecifics, or related modalities)