Senior Scientist, siRNA therapeutics

Qilu Pharmaceuticals is a leading pharmaceutical and biopharmaceutical company in China, with 3 innovation centers in the US. We are seeking highly motivated and experienced scientists with strong assay development expertise to join our collaborative and fast-growing RNA Therapy team.The successful candidate will play a key role in advancing innovative siRNA therapeutics for the treatment of serious diseases, including metabolic and liver diseases, neurological disorders, and ocular disease.Primary ResponsibilitiesLead and execute preclinical screening and evaluation of siRNA candidates to support lead identification and candidate selection through integrated in vitro and in vivo studiesInvestigate target biology and mechanism of action; design and conduct proof-of-concept studies to validate therapeutic targets in collaboration with internal teams and external partnersDevelop, optimize, and implement cellular and biochemical assays to support drug discovery and preclinical research activitiesCollaborate closely with cross-functional teams, including chemistry, non-clinical development, bioinformatics, and external CRO partnersManage multiple projects and priorities simultaneously while delivering high-quality results within established timelinesDemonstrate scientific creativity, critical thinking, and a strong commitment to innovationMaintain compliance with applicable SOPs and laboratory standards; provide technical guidance and training to junior team members as neededPresent scientific findings to project teams, leadership committees, and external collaborators. Communicate effectively across functions and organizational levelsQualifications and ExperiencePh.D. in Molecular Biology, Pharmacology, Neuroscience, or a related discipline, with: 3+ years of industry experience in biotechnology or pharmaceutical research; or 5+ years of relevant postdoctoral experience.Experience working with siRNA, ASO, or other oligonucleotide therapeutics is highly preferredExtensive hands-on experience with RT-qPCR, ELISA, Western blotting, mammalian cell culture, animal handling, tissue collection, and tissue processing is requiredPreferred technical skills include primary neuronal cell culture, stem-loop qPCR, and experience with rodent dosing techniques, including tail vein injection and intracranial administrationAdditional QualificationsDemonstrated record of scientific achievement through high-quality publications, patents, or drug discovery contributionsStrong experimental design, data analysis, and problem-solving skillsExcellent organizational and project management abilities, with a proven ability to work independently and manage multiple prioritiesThrives in a fast-paced, collaborative, and multidisciplinary research environment.Excellent verbal, written, and presentation skills