Associate Scientist, Protein Science

Soufflé Therapeutics | Associate Scientist | Job DescriptionSoufflé Therapeutics is a biotech company focusing on the cell-type specific delivery of genetic medicines. It's team of driven scientists is making a mark in delivery of oligonucleotides to extrahepatic tissues. We thrive in a purpose-building lab and office space in Watertown. Come and join us in our quest!Position Summary:Soufflé Therapeutics is growing its Protein Production team within Protein Science to increase throughput and capabilities and to build the redundancy that keeps work flowing for our project teams. As an Associate Scientist, you will produce antibodies and antibody-like proteins from mammalian cells to support our in vitro and in vivo studies. This is a new, hands-on role with direct impact on how quickly our programs move.Key ResponsibilitiesProduce different ligand formats, including antibodies and antibody-like proteins, from mammalian cells to support in vitro and in vivo studiesMaintain AKTA and other protein production instrumentationMaintain cells in culture for protein productionAnalyze and present data at group meetingsRepresent the protein production team at cross-functional meetingsWhat Success Looks LikeIn 3 months: Maintain cell cultures, purify your first proteins, and become acquainted with our instrumentation and ELN environmentIn 6 months: Use instrumentation independently, understand the production workflow, and be proficient in the ELN environmentIn 12 months: Deliver batches of proteins to project teams, understand Soufflé priorities, and present at group meetingsQualifications — Required1 to 2 years of relevant experience with an MS, or 2 to 3 years with a BSExperience with cell culture using aseptic technique, transient transfection, protein purification and chromatography, SDS-PAGE, Western blot, and UV absorbanceTeam-oriented and detail-oriented, with strong documentation, record keeping, and data analysis skillsEager to learn new things and comfortable working in a fast-paced environmentQualifications — PreferredProtein analytics experience: ELISA, BLI/SPR, HPLC, and thermal shift assaysMicrobiology experience: bacterial cell cultureMolecular biology experience: plasmid design and propagationEducationBS or MS in a relevant scientific disciplineAt Soufflé Therapeutics, we are intentional about building an equitable culture. How we treat our people is reflective of this focus. We are an Equal Opportunity Employer. We celebrate diversity and are committed to creating an inclusive environment for all employees.This is an onsite position in Watertown, MA (US) with flexibility as needed for collaboration and external engagements.