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Research Associate, Discovery Sciences

Avalon BioVentures · San Diego, CA

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ABOUT AVALON BIOVENTURES:Avalon BioVentures is a biotech venture capital firm that builds on Avalon’s 40-year success in pursuing disruptive ideas to improve life. From its established offices and labs on the Torrey Pines Mesa, in La Jolla, California, Avalon BioVentures leverages its Accelerator, which provides operational infrastructure and support, and the team’s extensive experience to identify promising science, build agile companies, and advance breakthrough therapeutics.ABOUT THE ROLEWe are seeking a highly motivated and detail-oriented Research Associate to join our team within the newest company in the Accelerator. This hands-on role is essential to the day-to-day operations of our laboratory. You will contribute directly to antibody production, biochemical and biophysical characterization. In addition to technical benchwork, you will play a key role in maintaining laboratory efficiency through consumables management, media preparation, and core laboratory support.KEY RESPONSIBILITIESMolecular Biology and Protein BiochemistryDevelop and run Molecular biology processes, including PCR, cloning, purification, quantification etc.Express, purify, and screen recombinant antibodies and proteins using standard platforms (e.g., mammalian cell culture, affinity chromatography).Perform biochemical and biophysical characterization using techniques such as SDS-PAGE, Western Blotting, SEC-HPLC, and thermal stability assays.Help troubleshoot purification protocols and routine analytical workflows to maintain high quality and yield.Cell-Based AssaysMaintain mammalian cell lines and primary-cell preparation/culture systems with consistent quality.Prepare reagents, controls and plates; support flow cytometry, ELISA/MSD/Luminex and other platform workflows as relevant.Capture and QC data, maintain accurate ELN documentation, and flag assay deviations or cell/reagent issues quickly.Laboratory Operations & ManagementManage laboratory inventory, including tracking, ordering, and restocking consumables, reagents, and media.Prepare common laboratory reagents, stock solutions, and cell culture media.Maintain, calibrate, and clean core laboratory equipment (e.g., biological safety cabinets, incubators, centrifuges).Coordinate lab dishwashing, sterilization (autoclaving), and biohazardous waste disposal.Ensure compliance with laboratory safety protocols, standard operating procedures (SOPs), and proper waste handling.REQUIRED EXPERIENCE